科普上層樓

難易度: ** 介紹新一波的研究正在揭示癌症和神經元之間的關係，並尋找可以阻止他們之間交流的方法。 #propranolol # calcitonin gene-related peptide, CGRP 請我喝杯咖啡吧https://open.firstory.me/join/science-up 小額贊助支持本節目： https://open.firstory.me/user/ckn4fdez1q4vv0874tetbieq1 留言告訴我你對這一集的想法： https://open.firstory.me/user/ckn4fdez1q4vv0874tetbieq1/comments Powered by Firstory Hosting

難易度: **** 介紹: 輝瑞新冠口服藥Paxlovid (nirmatrelvir/ ritonavir) 鹽野義新冠特效藥 Xocova (ensitrelvir) 先諾欣XIANNUOXIN (simnotrelvir/ ritonavir) #3C-like protease #3CL protease #Pfizer #Shionogi #Simcere #Molnupiravir #Lagevrio Paxlovid: Owen, D. R. et al. An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19. Science (2021); 374: 1586–1593. N Engl J Med. (2022); 14, 386(15):1397-1408. doi: 10.1056/NEJMoa2118542. Epub 2022 Feb 16. Xocova: Tyndall, J. D. A. S-217622, a 3CL protease inhibitor and clinical candidate for SARS-CoV-2. J. Med. Chem. (2022); 65: 6496–6498. Antimicrob Agents Chemother. (2022);18, 66(10): e0069722. doi: 10.1128/aac.00697-22. Epub 2022 Sep 13. XIANNUOXIN:  Jiang, X., Su, H., Shang, W. et al. Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir. Nat Commun (2023); 14: 6463. https://doi.org/10.1038/s41467-023-42102-y Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19 N Engl J Med (2024); 390: 230-241. DOI: 10.1056/NEJMoa2301425 請我喝杯咖啡吧https://open.firstory.me/join/science-up 小額贊助支持本節目： https://open.firstory.me/user/ckn4fdez1q4vv0874tetbieq1 留言告訴我你對這一集的想法： https://open.firstory.me/user/ckn4fdez1q4vv0874tetbieq1/comments Powered by Firstory Hosting

難易度: ** #化療 #掉髮 #TSLP #Thymic stromal lymphopoietin #CyclinD1 #Perseus Therapeutics #tezepelumab #Tezspire #AstraZeneca   請我喝杯咖啡吧https://open.firstory.me/join/science-up 小額贊助支持本節目： https://open.firstory.me/user/ckn4fdez1q4vv0874tetbieq1 留言告訴我你對這一集的想法： https://open.firstory.me/user/ckn4fdez1q4vv0874tetbieq1/comments Powered by Firstory Hosting

難易度:*** 1>Beta放射配體藥物: Zevalin: 90Y-anti-CD20 ibritumomab tiuxetan  Bexxar: 131I-anti-CD20 tositumomab Lutathera: 177Lu-anti-somatostatin receptor dodecanetetraacetic acid tyrosine-3-octreotate (DOTATATE) Pluvicto: 177Lu-PSMA-617 2>Alpha 放射配體藥物: Xofigo: RaCl2 RYZ101: 225Ac-anti-somatostatin receptor 2 (SSTR2) somatostatin analogue Actinium A: 225Ac-anti-CD33 Lintuzumab FPI-1434: 225Ac-anti-IGF-1R mAb #放射線治療 #放射線藥物 #放射配體 ＃radioligand therapy #RLT #Zevalin #Bexxar #Lutathera #Pluvicto # Xofigo #釔90 #碘131 #鎦177 #鐳227 #錒225 #砹211 #鉛212 #釷227 #RayzeBio #POINT Biopharma   請我喝杯咖啡吧https://open.firstory.me/join/science-up 小額贊助支持本節目： https://open.firstory.me/user/ckn4fdez1q4vv0874tetbieq1 留言告訴我你對這一集的想法： https://open.firstory.me/user/ckn4fdez1q4vv0874tetbieq1/comments Powered by Firstory Hosting

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